What is a closed-loop system?

'a close-up of a circuit board'

A closed-loop system is one where the activity from cells impacts an environment[1]. It includes feedback to the neural systems about the result of the system activity[2][3]. In this type of system, feedback is provided on the causal effects of the neuronal culture’s behavior[4]. Neural cultures are given a chance to process structured information and alter activity in meaningful and measurable ways[1].

[1] rsv.org.au