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Spicy food is not heat: how capsaicin tricks your pain receptors

Spicy food isn't "hot". Capsaicin hijacks TRPV1, the pain receptor that also detects dangerous heat, so your brain reads chili like a burn. Water just spreads it around; milk helps because casein can bind capsaicin.[1][2][19][20]

  • A video explains a chemical compound called capsaicin (molecular model shown right), which is found in chili peppers creates the ’burning’ sensation sometimes caused by spicy food. The compound binds to TRPV1 pain receptors in the mouth, (illustrated left) which detect heat
  • Glass of milk next to spicy chili peppers