Guess the Biotech Milestone Year

Q1. Which year marks Khorana and his coworkers completing the first laboratory synthesis of a complete gene? After a wrong attempt, reveal this hint: It was a chemically synthesized yeast transfer-RNA gene.[[cite:1]][[cite:2]].
- 1968
- 1970
- 1972
- 1975
Answer: 1972[[cite:3]][[cite:4]]
Q2. Which year refers to Paul Berg’s initial in-vitro construction of recombinant DNA molecules? After a wrong attempt, reveal this hint: Do not confuse this laboratory construction with the later bacterial experiment.[[cite:5]].
- 1970
- 1972
- 1973
- 1976
Answer: 1972[[cite:6]]
Q3. In which year did Cohen and Boyer perform the first successful recombinant DNA experiment using bacterial genes? After a wrong attempt, reveal this hint: This milestone followed the 1972 in-vitro construction of recombinant DNA molecules.[[cite:7]][[cite:8]].
- 1971
- 1972
- 1973
- 1974
Answer: 1973[[cite:9]][[cite:10]]
Q4. Which year is associated with the conception or development of the polymerase chain reaction? After a wrong attempt, reveal this hint: The milestone is linked to Kary Mullis.[[cite:11]][[cite:12]].
- 1978
- 1981
- 1983
- 1986
Answer: 1983[[cite:13]][[cite:14]]
Q5. Which year marks the first transgenic animals with a genetic change shown to pass to offspring? After a wrong attempt, reveal this hint: The work involved inserting foreign DNA into mouse embryos.[[cite:15]][[cite:16]].
- 1974
- 1978
- 1981
- 1984
Answer: 1981[[cite:17]][[cite:18]]
Q6. In which year did Genentech announce production of genetically engineered human insulin? After a wrong attempt, reveal this hint: This asks about production, not the FDA approval date.[[cite:19]][[cite:20]].
- 1975
- 1978
- 1980
- 1982
Answer: 1978[[cite:21]]
Q7. Which year marks FDA approval of Humulin, recombinant human insulin produced by engineered bacteria? After a wrong attempt, reveal this hint: The production milestone occurred in 1978, while approval came later.[[cite:22]][[cite:23]].
- 1978
- 1980
- 1982
- 1985
Answer: 1982[[cite:24]]

demonstrated by Har Gobind Khorana and coworkers in 1972.

Guess the Biotech Milestone Year

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