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Past ClinicalTrials.gov quality signals, not current performance
This is a retrospective look at registry quality signals in ClinicalTrials.gov, not a report of current performance.
The registry-record analysis examined 79,413 ClinicalTrials.gov records.
In the planned-analysis sample, 61% of first primary outcome entries were too vague to identify a measurement or domain.
The posted-results review analyzed 2,178 publicly posted results records.
Among posted results records, 20% reported more than two primary outcomes, and sponsors or investigators self-reported the data without an independent verification source.
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