How are biological risks mitigated?

Biological risks are mitigated through a comprehensive approach outlined in OpenAI’s Preparedness Framework. This includes implementing a multi-layered defense stack that combines model safety training, real-time automated monitoring, and robust system-level protections. The model is trained to refuse all requests for weaponization assistance and to avoid providing detailed actionable assistance on dual-use topics.

Additionally, account-level enforcement mechanisms are in place to identify and ban users attempting to leverage the model to create biological threats. This proactive monitoring aims to ensure that users cannot cause severe harm via persistent probing for biorisk content. Together, these measures help minimize the risks associated with biological capabilities in the deployed models^[1].