Yes, neurons can play games like Pong. Cortical Labs' original DishBrain prototype trained cell cultures to play Pong in a simulated environment[2]. The neurons learned to track the ball and control a paddle, demonstrating goal-oriented behavior in vitro[2]. In this instance, the neuronal cells on a synthetic chip appeared to have become goal-directed, a step closer to intelligence[1].
In a real-time closed-loop system, electrical stimulation was delivered into cultures of neural cells, telling the neural cells the x and y positions of the ball relative to the paddle[1]. In response to this stimulation, the cells produced electrical activity, which was read by the detector and used to move the paddle[1]. The result was that the neural cells appeared to self-organize their activity and got better at playing the game, supporting this as at least one driver behind intelligent behaviour[1].
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