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What neurotransmitter is most associated with haptic perception?
In the nervous system, tactile signals are transmitted using glutamate as a principal neurotransmitter at the first sensory synapses in the dorsal horn of the spinal cord and brainstem[1]. Additionally, research indicates that norepinephrine acts as a neurotransmitter for synaptic transmission from Merkel cells to secondary sensory neurons during gentle touch[2], while specific neuropeptides such as prokineticin 2 (PROK2) transmit pleasant touch signals[3].
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