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Nature Reviews Biodiversity | Volume 2 | April 2026 | 258–272 271 Roadmap 71. Government Gazette Republic of South Africa. National Environmental Management: Biodiversity Act, 2004 (No. 10 of 2004). gov.za https://www.gov.za/sites/default/files/ gcis_document/201409/a10-04.pdf (2004). 72. Laird, S. et al. Rethink the expansion of access and benefit sharing. Science 367, 1200–1202 (2020). 73. Tsioumani, E. et al. Summary of the 2024 UN Biodiversity Conference: 21 October – 1 November 2024. Earth Negot. Bull. 9, 1–21 (2024). 74. Levine, A. Convergence or convenience? International conservation NGOs and development assistance in Tanzania. World Dev. 30, 1043–1055 (2002). 75. Abebe, R. et al. Narratives and counternarratives on data sharing in Africa. In FAccT 2021 - Proc. 2021 ACM Conf. Fairness Account. Transpar., 329–341 (ACM, 2021). 76. African BioGenome Project. Inqaba Biotec and UNISA to launch Africa’s first PacBio Revio sequencing platform. africanbiogenome.org https://africanbiogenome.org/2024/07/17/ inqaba-biotec-and-unisa-to-launch-africas-first-pacbio-revio-sequencing-platform/ (2024). 77. Inqaba Biotec. Inqaba Biotec and UNISA launch Africa’s first PacBio Revio DNA sequencing platform. inqababiotec.co.za https://inqababiotec.co.za/2024/07/17/inqaba-biotec-and- unisa-launch-africas-first-pacbio-revio-dna-sequencing-platform/ (2024). 78. University of South Africa. Unisa and Inqaba Biotec unveil groundbreaking DNA research platform. unisa.ac.za https://www.unisa.ac.za/sites/corporate/default/ Colleges/Agriculture-&-Environmental-Sciences/News-&-events/Articles/Unisa- and-Inqaba-Biotec-unveil-groundbreaking-DNA-research-platform (2024). 79. 1KSA. 1KSA Decoding South Africa’s biodiversity. 1ksa.org.za https://www.1ksa.org.za (2026). 80. African BioGenome Project. Institutional partners – African BioGenome Project. africanbiogenome.org https://africanbiogenome.org/about-us/institutional-partners/ (2026). 81. Dosso, M., Cassi, L. & Mescheba, W. Towards regional scientific integration in Africa? Evidence from co-publications. Res. Policy 52, 104630 (2023). 82. African BioGenome Project. Sequencing in Africa: lessons learned from building chromosome-level plant genomes. africanbiogenomes.org https://africanbiogenome. org/2025/12/01/sequencing-in-africa-lessons-learned-from-building-chromosome-level- plant-genomes/ (2025). 83. McCartney, A. M. et al. The European Reference Genome Atlas: piloting a decentralised approach to equitable biodiversity genomics. NPJ Biodivers. 3, 28 (2024). 84. Parker-Allie, F., Gibbons, M. J. & Harebottle, D. M. A conceptual approach to developing biodiversity informatics as a field of science in South Africa. Front. Ecol. Evol. 11, 1107212 (2023). 85. UNESCO. The gender gap in science: status and trends, February 2024. unesco.org https://unesdoc.unesco.org/ark:/48223/pf0000388805 (2024). 86. African Union. AU strategy for gender equality & women’s empowerment. au.int http:// au.int/sites/default/files/documents/36195-doc-52569_au_strategy_eng_high.pdf (2018). 87. United Nations. Transforming our world: the 2030 agenda for sustainable development. un.org http://sdgs.un.org/2030agenda (2015). 88. African Women in Agricultural Research and Development. A decade of advancing inclusive agricultural research: the AWARD story. awardfellowships.org https:// awardfellowships.org/wp-content/uploads/2020/06/Final_AWARD@10_report_2018.pdf (2018). 89. Kariuki, T., Mutimura, E. & Kadzamira, G. Innovative approaches for unlocking R&D funding in Africa. World Economic Forum https://www.weforum.org/stories/2023/11/ innovative-approaches-for-unlocking-research-and-development-funding-in-africa/ (2023). 90. Badaoui, B. Economics of African biodiversity genomics and bioinformatics for prosperity. Preprint at Zenodo https://doi.org/10.5281/zenodo.18307246 (2026). 91. Wei, F. et al. Balancing community livelihoods and biodiversity conservation of protected areas in East Africa. Curr. Opin. Environ. Sustain. 33, 26–33 (2018). 92. Sintayehu, D. W. Impact of climate change on biodiversity and associated key ecosystem services in Africa: a systematic review. Ecosyst. Health Sustain. 4, 225–239 (2018). 93. Crisp, B. R., Swerissen, H. & Duckett, S. J. Four approaches to capacity building in health: consequences for measurement and accountability. Health Promot. Int. 15, 99–107 (2000). 94. Jacob, C. et al. A two way process – social capacity as a driver and outcome of equitable marine spatial planning. Mar. Policy 149, 105507 (2023). 95. Li, R., Ruiz, F., Culyer, A. J., Chalkidou, K. & Hofman, K. J. Evidence-informed capacity building for setting health priorities in low- and middle-income countries: a framework and recommendations for further research. F1000Research 6, 231 (2017). 96. Selemani, I. S. Indigenous knowledge and rangelands’ biodiversity conservation in Tanzania: success and failure. Biodivers. Conserv. 29, 3863 (2020). 97. Kosoe, E. A., Adjei, P. O. W. & Diawuo, F. From sacrilege to sustainability: the role of indigenous knowledge systems in biodiversity conservation in the Upper West Region of Ghana. GeoJournal 85, 1057–1074 (2020). 98. Sinthumule, N. I. Traditional ecological knowledge and its role in biodiversity conservation: a systematic review. Front. Environ. Sci. 11, 1164900 (2023). 99. United Nations. United Nations Declaration on the Rights of Indigenous Peoples. un.org https://social.desa.un.org/sites/default/files/migrated/19/2018/11/UNDRIP_E_web.pdf (2007). 100. Kouidhi, S. et al. Bridging data gaps: African reference genomes advancing inclusive microbiome research. Trends Microbiol. 33, 479–483 (2025). 101. Munung, N. S. Science and society: pathways to equitable access and delivery of genomics medicine in Africa. Curr. Genet. Med. Rep. 13, 492 (2025). 102. African Union. Agenda 2063: the Africa we want. au.int https://au.int/en/agenda2063/ overview (2013). 103. MEFT/NACSO. The state of community conservation in Namibia (annual report 2022). conservationnamibia.com https://conservationnamibia.com/other/meft-nacso-state- of-community-conservation-namibia-2022.pdf (2023). 104. Adebola, T. & Manzella, D. Access and benefit-sharing and digital sequence information in Africa: a critical analysis of contemporary concerns in regional governance. SSRN https://papers.ssrn.com/sol3/papers.cfm?abstract_id=4307587 (2022). 105. Waneyombo-Brachka, D. B. & Abada, M. M. M. Governance of Dzanga-Sangha protected areas in the Central African Republic: from an administrative approach to an inclusive local management approach. Nat. Faune 30, 53–55 (2016). 106. Multistakeholder Platform on Vaccine Security. The impact of the Nagoya Protocol on foot-and-mouth disease. fao.org https://openknowledge.fao.org/server/api/core/ bitstreams/bb1224bd-7cfb-4b89-a2f7-702fae2a9574/content (2023). 107. Knauf, S., Abel, L. & Hallmaier-Wacker, L. K. The Nagoya protocol and research on emerging infectious diseases. Bull. World Health Organ. 97, 379 (2019). 108. UNESCO. UNESCO Recommendation on Open Science. unesco.org https://unesdoc. unesco.org/ark:/48223/pf0000379949 (2021). 109. Angeles, N. A. C. & Catap, E. S. Challenges on the development of biodiversity biobanks: the living archives of biodiversity. Biopreserv. Biobank 21, 5–13 (2023). 110. Miserendino, A. R. A. et al. The case for community self-governance on access and benefit sharing of digital sequence information. BioScience 72, 405–408 (2022). 111. Tsioumanis, A. T., Hovden, K., Schabus, N. & Vovk, E. Summary of the 26th Meeting of the Subsidiary Body on Scientific, Technical and Technological Advice and the 4th Meeting of the Subsidiary Body on Implementation of the Convention on Biological Diversity: 13-29 May 2024. Earth Negot. Bull. 9, 1–26 (2024). 112. Daly, B. & Ranwashe, F. South Africa’s initiative toward an integrated biodiversity data portal. Front. Ecol. Evol. 11, 1124928 (2023). 113. Oliva, A. et al. Future-proofing genomic data and consent management: a comprehensive review of technology innovations. GigaScience 13, giae021 (2024). 114. Ring, I. & Barton, D. N. in Handbook of Ecological Economics (eds Martínez-Alier, J. & Muradian, R.) 413–449 (ElgarOnline, 2015). 115. Avilés-Polanco, G., Jefferson, D. J., Almendarez-Hernández, M. A. & Beltrán-Morales, L. F.
Factors that explain the utilization of the Nagoya Protocol Framework for Access and Benefit Sharing. Sustain. 11, 5550 (2019). 116. Maney, C. et al. National commitments to Aichi Targets and their implications for monitoring the Kunming-Montreal Global Biodiversity Framework. NPJ Biodivers. 2024 31, 1–8 (2024). 117. Lachenmeier, D. W. & Montagnon, C. Convention on Biological Diversity (CBD) and the Nagoya Protocol: implications and compliance strategies for the global coffee community. Foods 13, 254 (2024). 118. African Union Commission. African Union Strategic Guidelines for the Coordinated Implementation of the Nagoya Protocol on Access to Genetic Resources and the Fair and Equitable Sharing of Benefits Arising from their Utilisation (AU, 2015). 119. Katee, S. M. ELSI perspectives of the African BioGenome Project. cgiar.org http://cgspace. cgiar.org/bitstreams/853ddef9-4514-4d47-9067-c7bbacc1338b/download (2023). 120. Viergever, R. F. & Hendriks, T. C. C. The 10 largest public and philanthropic funders of health research in the world: what they fund and how they distribute their funds. Health Res. Policy. Syst. 14, 12 (2016). 121. Adam, T. et al. World RePORT: a database for mapping biomedical research funding. Lancet Glob. Health 8, e27–e29 (2020). 122. Tollefson, J., Garisto, D., Kozlov, M. & Witze, A. Trump proposes unprecedented budget cuts to US science. Nature 641, 565–566 (2025). 123. Murray, L. W. & Venter, F. The impact of United States Government cuts to funding on South African Healthcare and Research. Wits J. Clin. Med. 7, 87–90 (2025). 124. Vilaça, S. T. et al. Leveraging genomes to support conservation and bioeconomy policies in a megadiverse country. Cell Genomics 4, 100678 (2024). 125. NETFUND. National environment trust fund draft strategic plan 2023-2027. netfund.go.ke https://www.netfund.go.ke/wp-content/uploads/2024/05/ NETFUNDStrategicPlanMay212024_Final.pdf (2023). 126. Kaseya, J. et al. Tackling the twin threats of pandemics and climate change: an agenda for action. J. Public. Health Afr. 14, 2 (2023). 127. Omumbo, J., Kariuki, T., Ciugu, K. & Marincola, E. The interconnected global emergencies of climate change, food security and health: a call to action by the Science for Africa Foundation. Open Res. Afr. 6, 1 (2023). 128. Sosa, M. & Ivanova, A. Assessment of financing for biodiversity conservation in Mexico: links between biodiversity and climate change adaptation funds. Diversity 17, 185 (2025). 129. McKiernan, E. C. et al. Point of View: How open science helps researchers succeed. eLife 5, e16800 (2016). Acknowledgements This paper has benefited from the support and resources provided by the African BioGenome Project (AfricaBP). We would also like to thank V. Ras at the University of Cape Town, Cape Town, and the University of the Western Cape, Bellville, South Africa, for providing input in the initial draft and reviewing the final draft of the manuscript. This work is dedicated to the memory of
Dr Girish Beedessee, a valued co-author on this paper, who, with deep regret, passed away while the manuscript was under editorial consideration. Dr Beedessee was a lifelong contributor to the study of protists and their ecological roles, with a particular focus on adaptation and lifestyles. Since 2021, he had been a committed and valued member of the African BioGenome Project, serving on the Annotation Subcommittee. His scientific contributions and collegial spirit leave a lasting imprint on the field and those who had the privilege to work alongside him.

Nature Reviews Biodiversity | Volume 2 | April 2026 | 258–272 272 Roadmap Author contributions Conceived idea: S.M.K., M.B. and T.E.E.; literature review: S.M.K., M.B., T.E.E., B.B., S.P., A.W.T.M., S.I.N., J.A.N., S.B.S.G., I.H., D.N.O., A.S., S.M. and K.T.; questionnaire development and collection: J.E.I. and V.N.S.; questionnaire analysis: T.E.E., B.B. and G.B.; production of manuscript diagram: T.E.E., G.B. and A.E.A.; manuscript drafting: S.M.K., M.B., V.S., E.H.K.-N., A.E.A., S.B.S.G., I.H., D.N.O., A.S., S.M., K.T., F.J.B.M., S.C.E., C.E., H.G., R.O.-A. and C.R.T.; manuscript revision: S.M.K., M.B., J.E.I., T.E.E., B.B., S.P., A.W.T.M., S.I.N. and I.H.; supervision, oversight and leadership responsibilities: T.E.E.; journal correspondence: T.E.E.; manuscript review and approval: all authors. Competing interests J.E.I. is a Principal Investigator at MyAfroDNA. D.N.O. is a Consultant Bioinformatician at Eurekan Biotechnologies. Additional information Supplementary information The online version contains supplementary material available at
https://doi.org/10.1038/s44358-026-00143-3. Peer review information Nature Reviews Biodiversity thanks the anonymous reviewers for their contribution to the peer review of this work. Publisher’s note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law. Related links African BioGenome Project: https://africanbiogenome.org Cali Fund: https://www.cbd.int/califund Cartagena Protocol: https://bch.cbd.int/protocol Convention on Biological Diversity: https://www.cbd.int/ Global Alliance for Genomics and Health Passports: https://www.ga4gh.org/ Kunming-Montreal Global Biodiversity Framework: https://www.cbd.int/gbf Nagoya Protocol: https://www.cbd.int/abs © Springer Nature Limited 2026 1Centre for Tropical Livestock Genetics and Health (CTLGH) – International Livestock Research Institute (ILRI), Nairobi, Kenya. 2School of Law, University of KwaZulu-Natal, Durban, South Africa. 3Faculty of Sciences, Mohammed V University in Rabat, Rabat, Morocco. 4African Genome Center, University Mohammed VI Polytechnic (UM6P), Ben Guerir, Morocco. 5INFANT Research Centre, College of Medicine and Health, University College Cork, Cork, Ireland. 6Federal University of Lafia, Lafia, Nigeria. 7Department of Applied Sciences, Faculty of Health and Life Sciences, Northumbria University, London, UK. 8Neurogenetics of Language, The Rockefeller University, New York, NY, USA. 9Unit for Environmental Sciences and Management, North-West University, Potchefstroom, South Africa. 10African Sustainable Agriculture Research Institute (ASARI), Mohammed VI Polytechnic University (UM6P), Laâyoune, Morocco. 11Applied Genetics in Agriculture, Ecology and Public Health Laboratory, University of Tlemcen, Tlemcen, Algeria. 12School of Life Sciences, University of Warwick, Coventry, UK. 13Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, UK. 14Eurekan Biotechnologies, Plantation, Florida, USA. 15SequAna Core Facility, Department of Biology, University of Konstanz, Konstanz, Germany. 16Department of
Genetics, Faculty of Agriculture, Ain Shams University, Cairo, Egypt. 17Bio and Emerging Technology Institute (BETin), Addis Ababa, Ethiopia. 18Addis Ababa
University, Addis Ababa, Ethiopia. 19Finima Nature Park, Bonny Island, Nigeria. 20Department of Animal Science, School of Agriculture, University of Ghana, Accra, Ghana. 21Delta State University, Abraka, Nigeria. 22University of Cape Town, Cape Town, South Africa. 23School of Engineering, University of British Columbia – Okanagan, Kelowna, British Columbia, Canada. 24Science for Africa Foundation, Nairobi, Kenya. 25Bernhard-Nocht Institute of Tropical Medicine, Hamburg, Germany. 26Bioinformatics Laboratory, College of Computing, Mohammed VI Polytechnic University, Ben Guerir, Morocco. 27National Defence University-Kenya, Lanet, Kenya. 28Jomo Kenyatta University of Agriculture and Technology, Juja, Kenya. 29MyAfroDNA, Port Harcourt, Nigeria. 30African BioGenome Project (AfricaBP), Juja, Kenya. 31These authors contributed equally: Sally Mueni Katee, Marietjie Botes.

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